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January Journal Club

Speaker: Emma Pineau (Left)

Paper: Age differences in spontaneous cerebrovascular reactivity at rest

Learning Objectives:

  1. We will learn about spontaneous cerebrovascular reactivity (sCVR), derived from arterial spin labeling magnetic resonance imaging as a metric to describe vulnerability to vascular dysfunction 

  2. We will discuss the paper's findings of alterations in sCVR with age, in the absence of cognitive decline

  3. We will consider the implications of sCVR as a non-invasive, rapidly acquired metric, that may serve as an early biomarker of susceptibility to vascular dementia and related illnesses

About the Speaker: Emma is a PhD candidate in the Faculty of Medical Biophysics at the University of Toronto, supervised by Dr. Bojana Stefanovic and Dr. Maged Goubran. Her graduate research focuses on the substantial inter-individual variability in both the neurophysiological effects and clinical symptomatology of Alzheimer’s disease and related dementias. She aims to leverage this variability, together with advanced magnetic resonance imaging techniques, to develop methods for tailoring therapies to individual patients’ needs.

Speaker: Olayinka Akinrolie, PhD (Right)

Presentation Title: Is There a Link Between Vascular Risk Factors and Brain Changes in Older Adults with Attention-Deficit/Hyperactivity Disorder (ADHD)?

Learning Objectives:

  1. Describe white matter lesions and their relevance in attention-deficit/hyperactivity disorder (ADHD).

  2. Review the prevalence of vascular risk factors, including hypertension and diabetes, among adults with ADHD.

  3. Examine the current evidence linking vascular risk factors to white matter lesions in older adults, with a focus on individuals with ADHD.

About the Speaker: Olayinka Akinrolie, PhD, is a Postdoctoral Fellow in the Lifespan Brain Health Lab in the Department of Psychology at the University of Calgary, under the supervision of Dr. Brandy Callahan. His research focuses on physical activity, health promotion, and ADHD in older adults. His current work examines the interactive effects of physical activity and vascular risk factors on brain changes among adults with ADHD.

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December 11

Endothelial-driven cerebrovascular dysfunction in Alzheimer’s disease.

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January 29

Key Issues Facing 2SLGBTQIA+ People Living with Dementia and Their Carers